Effect of ripe fruit pulp extract of Cucurbita pepo Linn. in aspirin induced gastric and duodenal ulcer in rats.

نویسندگان

  • Sentu Sarkar
  • Debjani Buha
چکیده

A significant decrease in alkaline phosphatase (AP) activity and mucosal thickness and increase in ulcer index (UI) was observed in aspirin treated stomach and duodenum of albino rats. However, pretreatment with C. pepo fruit pulp extract for 14 consecutive days showed increase in AP activity and mucosal thickness along with decrease in UI, suggesting gastroduodenal protective and anti-ulcerogenic properties of C. pepo.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Experimental Evaluation of Ficus Recemosa Linn. Fruits Extract on Gastric Ulceration

The ethanolic extract of Ficus recemosa was evaluated for its anti-ulcer activity against pyloric ligation, aspirin and ethanol induced gastric ulcer in rats. The fruits extract and standard (Ranitidine, orally at a dose of 50mg/kg body weight) was administered orally at the dose of 100,200,400mg/kg body weight. It was found that Ficus recemosa fruits extract showed a dose dependent reduction i...

متن کامل

Evaluation of Antiulcer Activity of Whole Plant Extract of Malvastrum tricuspidatum in Experimental Animals

Malvastrum tricuspidatum is recommended in Ayurveda and Folklore Medicine for the management of gastric ulcers. Therefore, the purpose of the study was to investigate the antiulcer effect of whole plant extract of Malvastrum tricuspidatum (MTE) on ethanol (EtOH)-induced, aspirin (ASP)-induced, cold-restraint-stress (CRU) and pylorus--ligation(PL)-induced gastric ulcer models in rats. Aqueo...

متن کامل

Antiulcer Activity of Patol Churna against Experimental Gastro-duodenal Ulcers in Rats

Patol churna is a well known ayurvedic formulation of Trichosanthes cucumerina Linn. (cucurbitaceae) administered in case of number of alimentary and liver disorders. It is widely used in Indian folk medicine for variety of disease conditions. The aim of present study was to evaluate the antiulcer activity of 50% ethanolic extract of patol churna (PCE) using various experimental models of gastr...

متن کامل

Anti-Ulcer and anti-secretory Properties of the Butea Monosperma (Lam) Bark Extract with Relation to anti-oxidant Studies

To investigate the ulcer protective and antisecretory properties of the methanolic extract of Butea monosperma (BM) bark with relation to antioxidant studies. The study was done on male albino rats.   Gastric ulcers were induced by Aspirin, Alcohol and Pylorous ligation. Lansoprazole was used as the standard drug for comparison. The free radical scavenging potential of the bark of BM ...

متن کامل

Antiulcerogenic Effect of Zataria multiflora Boiss. on Cysteamine Induced Duodenal Ulcer in Rats

       Research advances during recent years offer new insight into therapy and the prevention of gastrointestinal ulcers by using medicinal plants. Flavonoids, tannins, triterpenoids, fatty acids and essential oils are among the most effective herbal constituents that have potential antiulcerogenic properties, and most of them could be found in Zataria multiflora. Z. multiflora</e...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Indian journal of experimental biology

دوره 46 9  شماره 

صفحات  -

تاریخ انتشار 2008